Key points about gallbladder cancer
A rare but aggressive cancer that begins in the gallbladder.
- Often linked to gallstones or chronic inflammation
- Early symptoms may be vague or absent
- Usually found at a later stage when treatment is more complex
- Surgery is the main treatment when possible
Gallbladder cancer causes
- Long-term gallbladder inflammation
- Presence of gallstones, especially large ones
- Gallbladder polyps
- Infections like salmonella
- Congenital abnormalities of the bile ducts
Gallbladder Cancer risk factors
Several factors can increase the likelihood of developing gallbladder cancer:
- Being female
- Older age, especially over 65
- Having gallstones or chronic gallbladder disease
- Obesity
- A family history of gallbladder or biliary tract cancer
- Exposure to toxic chemicals or smoking
Gallbladder Cancer symptoms
Symptoms often appear later in the disease and may resemble other digestive conditions.
- Upper right abdominal pain
- Nausea or vomiting
- Yellowing of the skin or eyes (jaundice)
- Appetite loss
- Weight loss without trying
- A feeling of fullness or bloating
Gallbladder Cancer Diagnosis
Diagnosis usually involves a combination of imaging tests, blood work and sometimes tissue sampling
- Ultrasound to evaluate the gallbladder
- CT scan or MRI to look for tumors or spread
- Blood tests for liver function and tumor markers
- Biopsy, sometimes during surgery
- Endoscopic procedures like ERCP
Gallbladder cancer treatment
Treatment plans vary depending on stage, spread and patient health.
- Surgical removal of the gallbladder
- Liver resection or removal of bile ducts if cancer has spread
- Chemotherapy to treat advanced cases
- Radiation therapy to target difficult areas
- Palliative support for comfort in late stages
When to seek care
See a doctor if you have persistent abdominal pain, changes in digestion or yellowing of the skin. Early evaluation is especially important if you have gallbladder problems or other risk factors.
- Unexplained pain in the upper right abdomen
- Nausea, vomiting or feeling bloated after eating
- Signs of jaundice
- History of gallstones or gallbladder surgery with abnormal findings
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