Key points about gallbladder cancer

A rare but aggressive cancer that begins in the gallbladder.

  • Often linked to gallstones or chronic inflammation
  • Early symptoms may be vague or absent
  • Usually found at a later stage when treatment is more complex
  • Surgery is the main treatment when possible

Gallbladder cancer causes

  • Long-term gallbladder inflammation
  • Presence of gallstones, especially large ones
  • Gallbladder polyps
  • Infections like salmonella
  • Congenital abnormalities of the bile ducts

Gallbladder Cancer risk factors

Several factors can increase the likelihood of developing gallbladder cancer:

  • Being female
  • Older age, especially over 65
  • Having gallstones or chronic gallbladder disease
  • Obesity
  • A family history of gallbladder or biliary tract cancer
  • Exposure to toxic chemicals or smoking

Gallbladder Cancer symptoms

Symptoms often appear later in the disease and may resemble other digestive conditions.

  • Upper right abdominal pain
  • Nausea or vomiting
  • Yellowing of the skin or eyes (jaundice)
  • Appetite loss
  • Weight loss without trying
  • A feeling of fullness or bloating

Gallbladder Cancer Diagnosis

Diagnosis usually involves a combination of imaging tests, blood work and sometimes tissue sampling

  • Ultrasound to evaluate the gallbladder
  • CT scan or MRI to look for tumors or spread
  • Blood tests for liver function and tumor markers
  • Biopsy, sometimes during surgery
  • Endoscopic procedures like ERCP

Gallbladder cancer treatment

Treatment plans vary depending on stage, spread and patient health.

  • Surgical removal of the gallbladder
  • Liver resection or removal of bile ducts if cancer has spread
  • Chemotherapy to treat advanced cases
  • Radiation therapy to target difficult areas
  • Palliative support for comfort in late stages

When to seek care

See a doctor if you have persistent abdominal pain, changes in digestion or yellowing of the skin. Early evaluation is especially important if you have gallbladder problems or other risk factors.

  • Unexplained pain in the upper right abdomen
  • Nausea, vomiting or feeling bloated after eating
  • Signs of jaundice
  • History of gallstones or gallbladder surgery with abnormal findings

 

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