Key points about ampullary mass
- An ampullary mass is a growth near the opening where bile and pancreatic fluids enter the intestine
- It may be benign (non-cancerous) or malignant (cancerous)
- This area is important for digestion and hormone flow
- Symptoms often appear when the mass blocks ducts
- Early diagnosis improves treatment options
Common related conditions
Ampullary mass causes
These growths usually form when cells in the ampulla area begin growing abnormally.
- Cell changes near the bile or pancreatic duct
- Long-term swelling or irritation in the ducts
- Inherited syndromes like FAP
- Rarely, tumors spreading from other organs
Ampullary mass risk factors
Certain conditions and traits can increase your risk.
- Being over 50
- Family history of gastrointestinal cancers
- Genetic disorders like Lynch syndrome
- Chronic pancreatitis or bile duct disease
Ampullary mass symptoms
The mass may block bile flow, leading to clear signs and symptoms.
- Jaundice (yellow skin or eyes)
- Belly pain or discomfort
- Nausea or vomiting
- Pale stool or dark urine
- Itching or weight loss
Ampullary mass diagnosis
Doctors use several tools to find the mass and figure out if it's cancer.
- Blood tests to check liver and pancreas health
- CT or MRI scans for detailed images
- Endoscopic ultrasound or ERCP (tube with camera)
- Biopsy to test the mass for cancer cells
Ampullary mass treatment
Treatment depends on the type, size and location of the mass.
- Surgery (often the Whipple procedure) to remove the tumor
- Endoscopic stents to open blocked ducts
- Chemotherapy or radiation for cancer treatment
- Symptom relief with medication
When to seek care
See a doctor if you experience:
- Yellow skin or eyes
- Stomach pain that won’t go away
- Unexplained weight loss
- Changes in stool color or dark urine